{"product_id":"cimetidine-s1845","title":"Cimetidine","description":"\u003cp\u003e\u003cstrong\u003eCimetidine\u003c\/strong\u003e is an antagonist of Histamine Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in inflammation and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Histamine Receptors, Cimetidine can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Histamine Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Cimetidine is appropriate when a defined chemical perturbant is needed to connect Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805359546713,"sku":"S1845-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805359579481,"sku":"S1845-1G","price":658.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Cimetidine-Tagamet-chemical-structure-S1845.gif?v=1776174116","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/cimetidine-s1845","provider":"Absource Diagnostics","version":"1.0","type":"link"}