{"product_id":"chronophin-pdxp-antibody-sc-f1229","title":"Chronophin\/PDXP Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eChronophin\/PDXP is a target of interest in many antibody-based workflows. Chronophin (CIN) is a HAD-type protein phosphatase, which primarily targets members of the actin-depolymerizing factor\/cofilin family as its cellular protein substrates. It regulates cytoskeletal dynamics by dephosphorylating cofilin in response to extracellular stimuli. It controls cofilin activity during cell division alongside SSH, albeit in a spatiotemporally distinct manner.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cell projection, cytoplasm, and cytoskeleton, which can matter when signal is compared across treatments or changing cell states. Following Chronophin\/PDXP across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eChronophin\/PDXP is commonly interpreted in the context of neuroscience research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cell projection, and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cell projection, and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for Chronophin\/PDXP. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in Chronophin\/PDXP reflect biology rather than handling. When interpreting Chronophin\/PDXP, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep Chronophin\/PDXP trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577668182361,"sku":"F1229-20UL","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577668215129,"sku":"F1229-100UL","price":319.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577668247897,"sku":"F1229-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1229-IHC1.jpg?v=1773599474","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/chronophin-pdxp-antibody-sc-f1229","provider":"Absource Diagnostics","version":"1.0","type":"link"}