{"product_id":"cd14-antibody-sc-f1070","title":"CD14 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eHuman monocyte differentiation antigen CD14 is a pattern recognition receptor (PRR) that enhances innate immune responses. It is well-known as a co-receptor for various Toll-like Receptors (TLRs), facilitating the transfer of bacterial cell wall products to TLRs to initiate signaling cascades both at the cell surface and within the endosomal compartment.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, golgi apparatus, membrane, and secreted, which can matter when signal is compared across treatments or changing cell states. Following CD14 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCD14 is commonly interpreted in the context of immunology, metabolism, and infectious disease research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, golgi apparatus, and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, golgi apparatus, and membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003ehost-response changes during infection or pathogen-associated stimulation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CD14. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CD14 reflect biology rather than handling. When interpreting CD14, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CD14 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577603498329,"sku":"F1070-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577603531097,"sku":"F1070-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577603563865,"sku":"F1070-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1070-wb.gif?v=1773599251","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/cd14-antibody-sc-f1070","provider":"Absource Diagnostics","version":"1.0","type":"link"}