{"product_id":"cay10444-e1158","title":"CAY10444","description":"\u003cp\u003e\u003cstrong\u003eCAY10444\u003c\/strong\u003e is an antagonist of S1P Receptors used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking S1P Receptors, CAY10444 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving S1P Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CAY10444 is appropriate when a defined chemical perturbant is needed to connect S1P Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804337119577,"sku":"E1158-5MG","price":156.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804337152345,"sku":"E1158-25MG","price":468.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57804337185113,"sku":"E1158-1ML\/DMSO","price":173.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1158-cay10444-chemical-structure.gif?v=1776166582","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/cay10444-e1158","provider":"Absource Diagnostics","version":"1.0","type":"link"}