{"product_id":"camonsertib-rp-3500-e1108","title":"Camonsertib (RP-3500)","description":"\u003cp\u003e\u003cstrong\u003eCamonsertib (RP-3500)\u003c\/strong\u003e is an inhibitor of ATR and ATM used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ATR and ATM, Camonsertib (RP-3500) can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ATR and ATM\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Camonsertib (RP-3500) is appropriate when a defined chemical perturbant is needed to connect ATR and ATM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804327584089,"sku":"E1108-5MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804327616857,"sku":"E1108-25MG","price":1936.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804327649625,"sku":"E1108-100MG","price":3901.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57804327682393,"sku":"E1108-1ML\/DMSO","price":665.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1108-rp-3500-chemical-structure.png?v=1776166504","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/camonsertib-rp-3500-e1108","provider":"Absource Diagnostics","version":"1.0","type":"link"}