{"product_id":"bt2-e2663","title":"BT2","description":"\u003cp\u003e\u003cstrong\u003eBT2\u003c\/strong\u003e is an inhibitor of BCL-2 used in studies of Apoptosis and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis in apoptosis and cancer models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting BCL-2, BT2 can be used to examine caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis. This context is compatible with apoptosis, viability, and caspase-readout assays and metabolic flux, enzyme-activity, and pathway-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving BCL-2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis and cancer models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, BT2 is appropriate when a defined chemical perturbant is needed to connect BCL-2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804603392345,"sku":"E2663-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804603425113,"sku":"E2663-25MG","price":291.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e2663-bt2-chemical-structure.gif?v=1776167821","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/bt2-e2663","provider":"Absource Diagnostics","version":"1.0","type":"link"}