{"product_id":"bsg-antibody-sc-f0982","title":"CD147 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eBSG is a target of interest in many antibody-based workflows. A cluster of differentiation 147 (CD147) is a glycoprotein originally that regulates Matrix Metalloproteinase (MMP) through cell-matrix and cell-cell interaction. It is located on chromosome 19. CD147 interacts with caveolin-1, monocarboxylate transporter, CD98, and β1 integrin and promotes various processes such as cell metabolism, proliferation, migration, and invasion. Depending on the literature source, BSG may also be discussed as CD147 and Basigin\/EMMPRIN.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cell projection, endoplasmic reticulum, and membrane, which can matter when signal is compared across treatments or changing cell states. Following BSG across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eBSG is commonly interpreted in the context of cancer, metabolism, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cell projection, and endoplasmic reticulum, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cell projection, and endoplasmic reticulum across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for BSG. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in BSG reflect biology rather than handling. When interpreting BSG, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep BSG trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577583182169,"sku":"F0982-20UL","price":159.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577583214937,"sku":"F0982-100UL","price":339.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577583247705,"sku":"F0982-2X100UL","price":499.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0982-IF.png?v=1773599152","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/bsg-antibody-sc-f0982","provider":"Absource Diagnostics","version":"1.0","type":"link"}