{"product_id":"bix-01294-trihydrochloride-s8006","title":"BIX-01294 Trihydrochloride","description":"\u003cp\u003e\u003cstrong\u003eBIX-01294 Trihydrochloride\u003c\/strong\u003e is an inhibitor of Histone Methyltransferases and Transferases used in studies of Autophagy and Epigenetic Regulation and related signaling programs. It is especially relevant in autophagy, cancer, and epigenetics models, where defined compound exposure can be linked to autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Histone Methyltransferases and Transferases, BIX-01294 Trihydrochloride can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Histone Methyltransferases and Transferases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Autophagy and Epigenetic Regulation and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, BIX-01294 Trihydrochloride is appropriate when a defined chemical perturbant is needed to connect Histone Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809568596313,"sku":"S8006-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809568629081,"sku":"S8006-50MG","price":409.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809568661849,"sku":"S8006-1G","price":1955.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809568694617,"sku":"S8006-1ML\/DMSO","price":186.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/bix01294-chemical-structure-s8006.gif?v=1776202183","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/bix-01294-trihydrochloride-s8006","provider":"Absource Diagnostics","version":"1.0","type":"link"}