{"product_id":"birabresib-otx015-s7360","title":"Birabresib (OTX015)","description":"\u003cp\u003e\u003cstrong\u003eBirabresib (OTX015)\u003c\/strong\u003e is an inhibitor of BET used in studies of Epigenetic Regulation. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting BET, Birabresib (OTX015) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving BET\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Birabresib (OTX015) is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809476878681,"sku":"S7360-2MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57809476911449,"sku":"S7360-10MG","price":439.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809476944217,"sku":"S7360-1G","price":3901.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809476976985,"sku":"S7360-1ML\/DMSO","price":274.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/OTX015-chemical-structure-s7360.gif?v=1776201283","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/birabresib-otx015-s7360","provider":"Absource Diagnostics","version":"1.0","type":"link"}