{"product_id":"belizatinib-tsr-011-s8511","title":"Belizatinib (TSR-011)","description":"\u003cp\u003e\u003cstrong\u003eBelizatinib (TSR-011)\u003c\/strong\u003e is an inhibitor of ALK and Trk Receptors used in studies of MAPK \/ ERK Signaling. It is especially relevant in cancer, cell signaling, and neuroscience models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ALK and Trk Receptors, Belizatinib (TSR-011) can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ALK and Trk Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Belizatinib (TSR-011) is appropriate when a defined chemical perturbant is needed to connect ALK and Trk Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809615749465,"sku":"S8511-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809615782233,"sku":"S8511-25MG","price":439.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/tsr-011-belizatinib-chemical-structure-S8511.gif?v=1776202878","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/belizatinib-tsr-011-s8511","provider":"Absource Diagnostics","version":"1.0","type":"link"}