{"product_id":"belinostat-pxd101-s1085","title":"Belinostat (PXD101)","description":"\u003cp\u003e\u003cstrong\u003eBelinostat (PXD101)\u003c\/strong\u003e is an inhibitor of HDAC used in studies of Autophagy and Epigenetic Regulation. It is especially relevant in autophagy, cancer, and epigenetics models, where defined compound exposure can be linked to autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HDAC, Belinostat (PXD101) can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HDAC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Autophagy and Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Belinostat (PXD101) is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805217005913,"sku":"S1085-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805217038681,"sku":"S1085-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805217071449,"sku":"S1085-100MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805217104217,"sku":"S1085-200MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805217136985,"sku":"S1085-1G","price":1444.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805217169753,"sku":"S1085-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Belinostat-PXD101-chemical-structure-S1085.gif?v=1776172873","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/belinostat-pxd101-s1085","provider":"Absource Diagnostics","version":"1.0","type":"link"}