{"product_id":"bay-87-2243-s7309","title":"BAY 87-2243","description":"\u003cp\u003e\u003cstrong\u003eBAY 87-2243\u003c\/strong\u003e is an inhibitor of HIF used in studies of Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses in angiogenesis, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HIF, BAY 87-2243 can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HIF\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Oxidative Stress Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, BAY 87-2243 is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809472258393,"sku":"S7309-10MG","price":173.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809472291161,"sku":"S7309-50MG","price":734.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57809472323929,"sku":"S7309-200MG","price":1464.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809472356697,"sku":"S7309-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809472389465,"sku":"S7309-1ML\/DMSO","price":242.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/BAY-87-2243-chemical-structure-s7309.gif?v=1776201193","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/bay-87-2243-s7309","provider":"Absource Diagnostics","version":"1.0","type":"link"}