{"product_id":"azd6482-s1462","title":"AZD6482","description":"\u003cp\u003e\u003cstrong\u003eAZD6482\u003c\/strong\u003e is an inhibitor of DNA-PK and PI3K beta and related targets used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA-PK and PI3K beta and related targets, AZD6482 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA-PK and PI3K beta and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AZD6482 is appropriate when a defined chemical perturbant is needed to connect DNA-PK and PI3K beta and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805291749721,"sku":"S1462-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57805291782489,"sku":"S1462-10MG","price":314.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805291815257,"sku":"S1462-50MG","price":953.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/AZD-6482-chemical-structure-S1462.gif?v=1776173573","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/azd6482-s1462","provider":"Absource Diagnostics","version":"1.0","type":"link"}