{"product_id":"azd5153-6-hydroxy-2-naphthoic-acid-s8344","title":"AZD5153 6-hydroxy-2-naphthoic acid","description":"\u003cp\u003e\u003cstrong\u003eAZD5153 6-hydroxy-2-naphthoic acid\u003c\/strong\u003e is an inhibitor of BET used in studies of Epigenetic Regulation. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting BET, AZD5153 6-hydroxy-2-naphthoic acid can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving BET\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AZD5153 6-hydroxy-2-naphthoic acid is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809602642265,"sku":"S8344-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809602675033,"sku":"S8344-25MG","price":481.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809602707801,"sku":"S8344-100MG","price":1444.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809602740569,"sku":"S8344-1G","price":6850.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809602773337,"sku":"S8344-1ML\/DMSO","price":303.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/azd5153-chemical-structure-S8344.gif?v=1776202616","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/azd5153-6-hydroxy-2-naphthoic-acid-s8344","provider":"Absource Diagnostics","version":"1.0","type":"link"}