{"product_id":"atp5o-antibody-sc-f2084","title":"ATP5O Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eATP5O, encodes the oligomycin sensitivity-conferring protein (OSCP), is a nuclear-encoded subunit of mitochondrial ATP synthase (Complex V) and plays a critical structural and functional role in oxidative phosphorylation. It is located at the top of the peripheral stalk of the ATP synthase complex, linking the membrane-embedded Fo proton channel to the F1 catalytic core in the mitochondrial matrix. Depending on the literature source, ATP5O may also be discussed as ATPO and ATP synthase peripheral stalk subunit OSCP.\u003c\/p\u003e\u003cp\u003eReported cellular context includes membrane, mitochondrion, and mitochondrioninnermembrane, which can matter when signal is compared across treatments or changing cell states. Following ATP5O across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eATP5O is commonly interpreted in the context of metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans membrane, mitochondrion, and mitochondrioninnermembrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between membrane, mitochondrion, and mitochondrioninnermembrane across matched conditions\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for ATP5O. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in ATP5O reflect biology rather than handling. When interpreting ATP5O, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep ATP5O trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577855648089,"sku":"F2084-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577855680857,"sku":"F2084-100UL","price":369.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577855713625,"sku":"F2084-2X100UL","price":549.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2084-IF.png?v=1773600149","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/atp5o-antibody-sc-f2084","provider":"Absource Diagnostics","version":"1.0","type":"link"}