{"product_id":"atorvastatin-calcium-ci-981-s2077","title":"Atorvastatin Calcium (CI-981)","description":"\u003cp\u003e\u003cstrong\u003eAtorvastatin Calcium (CI-981)\u003c\/strong\u003e is an inhibitor of HMG-CoA Reductase used in studies of Apoptosis and Autophagy and related signaling programs. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation in apoptosis, autophagy, and cancer models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HMG-CoA Reductase, Atorvastatin Calcium (CI-981) can be used to examine caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HMG-CoA Reductase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Autophagy and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Atorvastatin Calcium (CI-981) is appropriate when a defined chemical perturbant is needed to connect HMG-CoA Reductase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805409223001,"sku":"S2077-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"500 mg","offer_id":57805409255769,"sku":"S2077-500MG","price":756.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805409288537,"sku":"S2077-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805409321305,"sku":"S2077-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Atorvastatin-calcium-chemical-structure-s2077.gif?v=1776174460","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/atorvastatin-calcium-ci-981-s2077","provider":"Absource Diagnostics","version":"1.0","type":"link"}