{"product_id":"ar7-s6605","title":"AR7","description":"\u003cp\u003e\u003cstrong\u003eAR7\u003c\/strong\u003e is an inhibitor of Retinoid Receptors used in studies of Apoptosis and Hormone Signaling. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and ligand-dependent transcriptional programs and endocrine regulation in apoptosis, cancer, and developmental biology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Retinoid Receptors, AR7 can be used to examine caspase-associated cell-death signaling and survival decisions and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Retinoid Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AR7 is appropriate when a defined chemical perturbant is needed to connect Retinoid Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809398989145,"sku":"S6605-5MG","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809399021913,"sku":"S6605-25MG","price":291.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6605-ar7.gif?v=1776200165","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ar7-s6605","provider":"Absource Diagnostics","version":"1.0","type":"link"}