{"product_id":"apararenone-e1239","title":"Apararenone","description":"\u003cp\u003e\u003cstrong\u003eApararenone\u003c\/strong\u003e is an antagonist of Mineralocorticoid Receptor used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in cardiovascular and endocrinology models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Mineralocorticoid Receptor, Apararenone can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Mineralocorticoid Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Apararenone is appropriate when a defined chemical perturbant is needed to connect Mineralocorticoid Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804364284249,"sku":"E1239-5MG","price":175.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804364317017,"sku":"E1239-25MG","price":527.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1239-apararenone-mt-3995-chemical-structure.png?v=1776166694","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/apararenone-e1239","provider":"Absource Diagnostics","version":"1.0","type":"link"}