{"product_id":"anln-antibody-sc-f3667","title":"Anillin Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eANLN is a target of interest in many antibody-based workflows. Anillin is a conserved scaffolding protein that plays critical roles in cytoskeletal organization and cellular processes. Structurally, it contains multiple functional domains, including an N-terminal actin-binding domain, a central anillin homology domain (AHD) that binds RhoA and microtubules, and a C-terminal pleckstrin homology (PH) domain for septin and phospholipid interactions. Depending on the literature source, ANLN may also be discussed as Anillin.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell projection, cytoplasm, cytoskeleton, and nucleus, which can matter when signal is compared across treatments or changing cell states. Following ANLN across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eANLN is commonly interpreted in the context of cancer, cell cycle, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell projection, cytoplasm, and cytoskeleton, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell projection, cytoplasm, and cytoskeleton across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in abundance, timing, or compartmental enrichment\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for ANLN. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in ANLN reflect biology rather than handling. When interpreting ANLN, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep ANLN trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578038919513,"sku":"F3667-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578038952281,"sku":"F3667-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578038985049,"sku":"F3667-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3667-IF.png?v=1773601379","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/anln-antibody-sc-f3667","provider":"Absource Diagnostics","version":"1.0","type":"link"}