{"product_id":"amprenavir-vx-478-s1639","title":"Amprenavir (VX-478)","description":"\u003cp\u003e\u003cstrong\u003eAmprenavir (VX-478)\u003c\/strong\u003e is an inhibitor of HIV Protease and PXR used in studies of Viral Entry \/ Replication and Metabolic Signaling. In practice, this places the compound in experiments that measure host-pathogen interactions, entry mechanisms, and replication-associated responses and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology, infectious disease, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HIV Protease and PXR, Amprenavir (VX-478) can be used to examine host-pathogen interactions, entry mechanisms, and replication-associated responses and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In endocrinology, infectious disease, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HIV Protease and PXR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Viral Entry \/ Replication and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eProtease-activity, cleavage, and substrate-processing assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Amprenavir (VX-478) is appropriate when a defined chemical perturbant is needed to connect HIV Protease and PXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, infectious disease, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805327204697,"sku":"S1639-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805327237465,"sku":"S1639-25MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Amprenavir-Agenerase-chemical-structure-S1639.gif?v=1776173843","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/amprenavir-vx-478-s1639","provider":"Absource Diagnostics","version":"1.0","type":"link"}