{"product_id":"amd3100-plerixafor-s8030","title":"AMD3100 (Plerixafor)","description":"\u003cp\u003e\u003cstrong\u003eAMD3100 (Plerixafor)\u003c\/strong\u003e is an antagonist of CXCR used in studies of Immune Signaling and Viral Entry \/ Replication and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses and host-pathogen interactions, entry mechanisms, and replication-associated responses in immunology, inflammation, and infectious disease models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking CXCR, AMD3100 (Plerixafor) can be used to examine cytokine-mediated signaling and inflammatory effector responses and host-pathogen interactions, entry mechanisms, and replication-associated responses. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CXCR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and Viral Entry \/ Replication and related signaling programs\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, AMD3100 (Plerixafor) is appropriate when a defined chemical perturbant is needed to connect CXCR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809570890073,"sku":"S8030-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57809570922841,"sku":"S8030-10MG","price":242.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809570955609,"sku":"S8030-50MG","price":560.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809570988377,"sku":"S8030-1G","price":2938.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Plerixafor-chemical-structure-s8030.gif?v=1776202217","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/amd3100-plerixafor-s8030","provider":"Absource Diagnostics","version":"1.0","type":"link"}