{"product_id":"alpha-tubulin-antibody-sc-f0620","title":"Acetyl-α-Tubulin (Lys40) Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eALPHA-TUBULIN is a target of interest in many antibody-based workflows. Acetyl-α-tubulin (Lys40) is a post-translationally modified form of α-tubulin characterized by the acetylation of lysine 40, located on the luminal surface of microtubules. This modification, catalyzed by α-tubulin acetyltransferase 1 (αTAT1), occurs away from the binding sites of most microtubule-associated proteins (MAPs) and motors, but αTAT1 itself can interact with the microtubule’s exterior via the tubulin C-termini. Depending on the literature source, ALPHA-TUBULIN may also be discussed as Acetyl-alpha-Tubulin (Lys40) and Acetylated Tubulin.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm, cytoskeleton, and microtubule, which can matter when signal is compared across treatments or changing cell states. Following ALPHA-TUBULIN across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eALPHA-TUBULIN is commonly interpreted in the context of neuroscience research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm, cytoskeleton, and microtubule, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm, cytoskeleton, and microtubule across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003edifferences between total target abundance and site-specific regulation when modified forms are compared\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for ALPHA-TUBULIN. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in ALPHA-TUBULIN reflect biology rather than handling. When interpreting ALPHA-TUBULIN, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep ALPHA-TUBULIN trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577492087129,"sku":"F0620-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577492119897,"sku":"F0620-100UL","price":419.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577492152665,"sku":"F0620-2X100UL","price":629.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0620-IF.png?v=1773598704","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/alpha-tubulin-antibody-sc-f0620","provider":"Absource Diagnostics","version":"1.0","type":"link"}