{"product_id":"4-ipp-s2643","title":"4-IPP","description":"\u003cp\u003e\u003cstrong\u003e4-IPP\u003c\/strong\u003e is an inhibitor of NF-kB used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NF-kB, 4-IPP can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NF-kB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, 4-IPP is appropriate when a defined chemical perturbant is needed to connect NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805686899033,"sku":"S2643-5MG","price":321.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805686931801,"sku":"S2643-25MG","price":822.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805686964569,"sku":"S2643-100MG","price":1815.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805686997337,"sku":"S2643-1G","price":4904.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805687030105,"sku":"S2643-1ML\/DMSO","price":390.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/4-ipp-chemical-structure-s2643.gif?v=1776175453","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/4-ipp-s2643","provider":"Absource Diagnostics","version":"1.0","type":"link"}