{"product_id":"1-nm-pp1-s6383","title":"1-NM-PP1","description":"\u003cp\u003e\u003cstrong\u003e1-NM-PP1\u003c\/strong\u003e is an inhibitor of SRC and CDK2 used in studies of MAPK \/ ERK Signaling and Cell Cycle Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing in angiogenesis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting SRC and CDK2, 1-NM-PP1 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving SRC and CDK2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Cell Cycle Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, 1-NM-PP1 is appropriate when a defined chemical perturbant is needed to connect SRC and CDK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809372414297,"sku":"S6383-5MG","price":164.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809372447065,"sku":"S6383-25MG","price":498.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6383-1-nm-pp1-chemical-structure.gif?v=1776199753","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/1-nm-pp1-s6383","provider":"Absource Diagnostics","version":"1.0","type":"link"}